Debutant Ben Healy guided Edinburgh to victory over the Dragons while Connacht, the Stormers and Ulster also sealed wins over the Ospreys, Lions and Zebre respectively.
The United Rugby Championship faces an uncertain future in the short-term after its UK broadcaster, Viaplay, announced their intention to sell off those rights.
Sam Warburton has his say on the state of Welsh Rugby following their recent financial issues and whether the four regions can show an improvement next season.
URC boss Martin Anayi has confirmed that Champions Cup qualification will revert to 'straight meritocracy' next season while the home final format remains.
Leinster suffered their first defeat of the season, conceding over 50 points for the first time in seven years, going down 62-7 to the Bulls in the URC.
Tom Stewart scored three tries, breaking the URC record, as Ulster beat the Dragons 40-19 on Friday with the Sharks and Glasgow Warriors claiming wins.
Leinster have announced that hooker Ronan Kelleher has signed a new deal at the province while scrum-half Dane Blacker will leave Scarlets for Dragons.